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There are now studies looking at CKD [chronic kidney disease] improvement as well as [better] cardiac outcomes.
At doses ranging from 40 to 200 mg taken twice daily, the highest weight reduction achieved was up to 11.7% compared to a 1.4% weight increase in the placebo group
Its use outside of authorised clinical trials is therefore unlicensed and unregulated
Kv1.5 channels are regulated by PKC-mediated endocytic degradation
GLP-1-based therapies carry recognised class-effect risks including pancreatitis, gallbladder disease, and gastrointestinal adverse effects requiring urgent medical attention if they occur
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