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The V3-V4 hypervariable region of the 16S rRNA gene was PCR-amplified with primer pairs 343F (5-TACGGRAGCAGCAG-3) and 798R (5-AGGGTATCTAATCCT-3)

Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial Clinical limits of amyotrophic lateral sclerosis workshop contributors

Variants of A complexed with Cu(II), including A(1-16), A(1-28), A(1-40), and A(1-42), can catalyze ROS production in the presence of ascorbate, with A(1-42) being the most efficient ROS generator 13

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Note that these observations are based on case reports, and do not necessarily reflect susceptibility of these demographics to toxicity (Amar 2007)

This product is handled exclusively in controlled research settings for in vitro and pre-clinical studies, with no applications in human or veterinary medicine