Most patients notice reduced hunger and increased fullness within 37 days of their first injection, though the appetite-suppressing effect builds over 46 weeks as your dose increases
For example, the SELECT trial revealed that patients on semaglutide maintained an average weight loss of -10.2% over four years (208 weeks), while the placebo group only saw a modest -1.5% reduction
The standard dose titration schedulestarting at a low dose and gradually increasing every 4 weeksis specifically designed to minimize gastrointestinal side effects by allowing the digestive system time to adapt
However, the risk increases when tirzepatide is combined with insulin or sulphonylureas, and dose reductions of these medications may be necessary
Use of multivitamins, intake of B vitamins and risk of ovulatory infertility
and take time eating slowly