Because oral options sit directly within the stomach to be absorbed, some patients report a higher frequency of upper gastrointestinal symptoms, including acid reflux, indigestion, and localised stomach discomfort during the morning fasting window
Yes, several dietary strategies and supplements have been shown to boost GLP-1 production, including high-protein foods, olive oil, fermentable fiber, allulose, berberine, EGCG, and curcumin
Our purpose is not to endorse or suggest the use of specific therapies, but to provide information about the evidence, or lack thereof, along with potential risks/benefits of various treatment modalities
GLP-1s: Lower blood sugar Reduce appetiteso you eat less and feel fuller Promote healthy weight loss Improve metabolism Lower whole-body inflammationincluding that which affects your joints GLP-1s Target Both Metabolic and Inflammatory Pathways Recent research shows that GLP-1 medications can: Lower levels of inflammatory cytokines like TNF-alpha, IL-6, and IL-1 Restore a healthier gut microbiome and calm immune reactions Reduce fat-driven inflammationwhy losing just 510% of body weight improves autoimmune diseases Reverse insulin resistancea key link between metabolic and autoimmune disease Reduce oxidative stress, protecting organs and joint cartilage GLP-1s in RA, PsA, OA, and More: Evidence and Results Rheumatoid Arthritis Obesity increases RA risk and severity
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3 In separate clinical studies of adults with overweight or obesity, about 1 in 4 taking Wegovy oral semaglutide 25 mg (64 weeks) and about 1 in 3 taking Wegovy injection 2.4 mg (68 weeks) lost 20% of body weight, alongside diet and exercise