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Underlying hormonal conditions, such as thyroid dysfunction, insulin resistance, or perimenopause, may also slow weight loss

And some work on the growth hormone axis to restore the body composition regulation that estrogen used to support

Weeks 3 to 6: When Patients Notice the Waistline Shift By weeks three to six, the cumulative lipolytic effect on visceral fat begins to produce visible changes

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This is mainly due to the growing consumption of GLP-1 drugs for diabetes management and a strong pipeline further supporting growth

The mechanism makes sense