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Betaine is also known as trimethylglycine
R.KaminskasL
These actions underscore active regulatory oversight
M.MatunisM
Some studies suggest the quinolinium structure is sufficiently NNMT-selective that it should not broadly deplete SAM, but the wider metabolic picture remains an active research consideration
At normal therapeutic doses (up to 3,0004,000 mg/day in adults), hepatic glutathione stores are typically adequate for NAPQI neutralization and rapid regeneration
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