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[16] Pruritus vulvae has been reported infrequently with tamoxifen use in patients with metastatic breast cancer

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Semaglutide has a half-life of approximately 7 days, so a washout of 2 to 3 weeks allows blood levels to drop to minimal levels

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This effect may attenuate over time (tachyphylaxis) and can affect the absorption of concomitant oral medicines, necessitating review of medication timing