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For protein digestion, 0.5 g of trypsin (Promega) was added to the samples, followed by an overnight incubation at 37 C
So, first, I completely agree GLP-1 agonists absolutely cause gastrointestinal side effects
Additionally, the non-enzymatic inter-conversion between GSSG and GSSR can occur
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Potential Side Effects and Safety Considerations Gastrointestinal adverse effects are the most commonly reported side effects of GLP-1 receptor agonists, occurring in a significant proportion of patients, particularly during treatment initiation and dose escalation
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