Reappraising the relationship between hyperinsulinemia and insulin resistance in PCOS
Acta biologica Hungarica 68, 334344
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found that these two vectors were highly expressed in myocardial mitochondria and showed that inhibition of DIC and OGC increased mitochondrial ROS and GSH depletion, exacerbating ferroptosis in the myocardium [60]
Anti-inflammatory properties of NRF2 signaling have been verified in LPS-stimulated mouse microglia, where its upregulation reduced inflammatory markers (Townsend and Johnson, 2016) and astrocytic, and microglial activation were found to be significantly lower (Jing et al., 2015)