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Notably, bi-allelic MC4R mutation carriers had long-term outcomes as poor as those with bi-allelic LEPR or POMC mutations, suggesting that biallelic mutations in LMP genes generally lead to more severe impairment of surgical efficacy compared to heterozygous mutations
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The evidence does not establish that liposomal or S-acetyl glutathione is universally superior, and product recommendations should reflect individual need, quality, tolerance and clinical context
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