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P-38 Impact of sex on the course of hereditary angioedema due to C1-inhibitor deficiency Hanga Rka Horvth, Lili Voloncs-Mindszenthy, Henriette Farkas Hungarian Angioedema Center of Reference and Excellence, Department of Internal Medicine and Haematology, Semmelweis University, Budapest, Hungary Allergy, Asthma & Clinical Immunology 2025, 21(Suppl 2) :P-38 Background: Although hereditary angio-edema (HAE) due to C1-inhibitor (C1-INH) deficiency (HAE-C1-INH) is inherited in an autosomal dominant manner, several reports have been published on female predominance in this disease (1, 2)

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All neurodegenerative diseases exhibit significant metabolic impairment, including decreased glucose uptake or utilization, with a consequent diminution in ATP production (59)

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Endocrinology 136:35853596 Kieffer TJ, Heller RS, Leech CA, Holz GG, Habener JF (1997) Leptin suppression of insulin secretion by activation of ATP-sensitive K + channels in pancreatic -cells

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