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Intravenous (IV) administration of glutathione allows for direct delivery into the bloodstream, bypassing the digestive system and ensuring rapid absorption
After extensive experiments, MC3181 was deemed the more promising compound of the two, due to it having a 50-fold rise in aqueous solubility and higher selectivity toward GST
This revelation reveals exciting possibilities in the realm of drug discovery, as GST inhibitors and its prodrugs offer a feasible strategy in designing anticancer drugs with the primary purpose of reversing tumor resistance
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