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Effects of exenatide and lifestyle modification on body weight and glucose tolerance in obese subjects with and without prediabetes

This third mechanism is what gives retatrutide its potential edge over existing treatments

The metabolic inflammation coming from fat tissue is undercutting it in real time

PMID 29439603

These gastrointestinal issues are similar to those seen with other GLP-1 receptor agonists but may be more pronounced due to the dual-action nature of Tirzepatide