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Intestinal permeabilitet: Leaky gut kt passasje av bakterier og toksiner gjennom tarmveggen er assosiert med systemisk inflammasjon, autoimmune tilstander og idrettsprestasjon

It also raised CD4 T-cell proportions in the bone marrow and modulated splenic CD8 cells, indicating rejuvenation toward a younger immune phenotype [5]

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More severe hepatotoxicity is attributed to additive effects of tissue autoantigen release due to tumor infiltration and also viral damage in conjunction with ICI-induced the autoreactive T cell activity